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The Role of Endoplasmic Reticulum Stress in Human Pathology

Numerous genetic and environmental insults impede the ability of cells to properly fold and posttranslationally modify secretory and transmembrane proteins in the endoplasmic reticulum (ER), leading to a buildup of misfolded proteins in this organelle—a condition called ER stress. ER-stressed cells...

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Bibliografski detalji
Izdano u:Annu Rev Pathol
Glavni autori: Oakes, Scott A., Papa, Feroz R.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568783/
https://ncbi.nlm.nih.gov/pubmed/25387057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pathol-012513-104649
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