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The Role of Endoplasmic Reticulum Stress in Human Pathology
Numerous genetic and environmental insults impede the ability of cells to properly fold and posttranslationally modify secretory and transmembrane proteins in the endoplasmic reticulum (ER), leading to a buildup of misfolded proteins in this organelle—a condition called ER stress. ER-stressed cells...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Annu Rev Pathol |
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| Κύριοι συγγραφείς: | , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2014
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5568783/ https://ncbi.nlm.nih.gov/pubmed/25387057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pathol-012513-104649 |
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