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The Role of Endoplasmic Reticulum Stress in Human Pathology
Numerous genetic and environmental insults impede the ability of cells to properly fold and posttranslationally modify secretory and transmembrane proteins in the endoplasmic reticulum (ER), leading to a buildup of misfolded proteins in this organelle—a condition called ER stress. ER-stressed cells...
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| 出版年: | Annu Rev Pathol |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5568783/ https://ncbi.nlm.nih.gov/pubmed/25387057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pathol-012513-104649 |
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