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The Role of Endoplasmic Reticulum Stress in Human Pathology

Numerous genetic and environmental insults impede the ability of cells to properly fold and posttranslationally modify secretory and transmembrane proteins in the endoplasmic reticulum (ER), leading to a buildup of misfolded proteins in this organelle—a condition called ER stress. ER-stressed cells...

詳細記述

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書誌詳細
出版年:Annu Rev Pathol
主要な著者: Oakes, Scott A., Papa, Feroz R.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568783/
https://ncbi.nlm.nih.gov/pubmed/25387057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pathol-012513-104649
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