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Signaling Cell Death from the Endoplasmic Reticulum Stress Response
Inability to meet protein folding demands within the endoplasmic reticulum (ER) activates the unfolded protein response (UPR), a signaling pathway with both adaptive and apoptotic outputs. While some secretory cell types have a remarkable ability to increase protein folding capacity, their upper lim...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3078187/ https://ncbi.nlm.nih.gov/pubmed/21146390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2010.11.003 |
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