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Mitochondria and lipid raft-located F(O)F(1)-ATP synthase as major therapeutic targets in the antileishmanial and anticancer activities of ether lipid edelfosine
BACKGROUND: Leishmaniasis is the world’s second deadliest parasitic disease after malaria, and current treatment of the different forms of this disease is far from satisfactory. Alkylphospholipid analogs (APLs) are a family of anticancer drugs that show antileishmanial activity, including the first...
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| Udgivet i: | PLoS Negl Trop Dis |
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| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5568728/ https://ncbi.nlm.nih.gov/pubmed/28829771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005805 |
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