Mitochondria and lipid raft-located F(O)F(1)-ATP synthase as major therapeutic targets in the antileishmanial and anticancer activities of ether lipid edelfosine

BACKGROUND: Leishmaniasis is the world’s second deadliest parasitic disease after malaria, and current treatment of the different forms of this disease is far from satisfactory. Alkylphospholipid analogs (APLs) are a family of anticancer drugs that show antileishmanial activity, including the first...

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書目詳細資料
發表在:PLoS Negl Trop Dis
Main Authors: Villa-Pulgarín, Janny A., Gajate, Consuelo, Botet, Javier, Jimenez, Alberto, Justies, Nicole, Varela-M, Rubén E., Cuesta-Marbán, Álvaro, Müller, Ingrid, Modolell, Manuel, Revuelta, José L., Mollinedo, Faustino
格式: Artigo
語言:Inglês
出版: Public Library of Science 2017
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568728/
https://ncbi.nlm.nih.gov/pubmed/28829771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005805
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