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Involvement of Raft Aggregates Enriched in Fas/CD95 Death-Inducing Signaling Complex in the Antileukemic Action of Edelfosine in Jurkat Cells

BACKGROUND: Recent evidence suggests that co-clustering of Fas/CD95 death receptor and lipid rafts plays a major role in death receptor-mediated apoptosis. METHODOLOGY/PRINCIPAL FINDINGS: By a combination of genetic, biochemical, and ultrastructural approaches, we provide here compelling evidence fo...

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Bibliografski detalji
Glavni autori: Gajate, Consuelo, Gonzalez-Camacho, Fernando, Mollinedo, Faustino
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662410/
https://ncbi.nlm.nih.gov/pubmed/19352436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005044
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