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A High-Throughput Process for the Solid-Phase Purification of Synthetic DNA Sequences

An efficient process for the purification of synthetic phosphorothioate and native DNA sequences is presented. The process is based on the use of an aminopropylated silica gel support functionalized with aminooxyalkyl functions to enable capture of DNA sequences through an oximation reaction with th...

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Foilsithe in:Curr Protoc Nucleic Acid Chem
Main Authors: Grajkowski, Andrzej, Cieślak, Jacek, Beaucage, Serge L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568675/
https://ncbi.nlm.nih.gov/pubmed/28628204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpnc.31
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