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A High-Throughput Process for the Solid-Phase Purification of Synthetic DNA Sequences

An efficient process for the purification of synthetic phosphorothioate and native DNA sequences is presented. The process is based on the use of an aminopropylated silica gel support functionalized with aminooxyalkyl functions to enable capture of DNA sequences through an oximation reaction with th...

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Dades bibliogràfiques
Publicat a:Curr Protoc Nucleic Acid Chem
Autors principals: Grajkowski, Andrzej, Cieślak, Jacek, Beaucage, Serge L.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568675/
https://ncbi.nlm.nih.gov/pubmed/28628204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpnc.31
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