Human beta-globin mRNAs that harbor a nonsense codon are degraded in murine erythroid tissues to intermediates lacking regions of exon I or exons I and II that have a cap-like structure at the 5' termini.

Lignende værker

• Nonsense codons in human beta-globin mRNA result in the production of mRNA degradation products.
  af: Lim, S K, et al.
  Udgivet: (1992)
• Novel metabolism of several beta zero-thalassemic beta-globin mRNAs in the erythroid tissues of transgenic mice.
  af: Lim, S, et al.
  Udgivet: (1989)
• β-Globin mRNA decay in erythroid cells: UG site-preferred endonucleolytic cleavage that is augmented by a premature termination codon
  af: Stevens, Audrey, et al.
  Udgivet: (2002)
• SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoan
  af: Huntzinger, Eric, et al.
  Udgivet: (2008)
• Evidence that the decay of nucleus-associated nonsense mRNA for human triosephosphate isomerase involves nonsense codon recognition after splicing.
  af: Zhang, J, et al.
  Udgivet: (1996)