Novel metabolism of several beta zero-thalassemic beta-globin mRNAs in the erythroid tissues of transgenic mice.

Mice that are transgenic for human beta zero-thalassemic beta-globin alleles were generated in order to study how beta zero-thalassemic mutations affect beta-globin RNA metabolism in erythroid tissues. Three thalassemic alleles were studied, each of which harbors either a frameshift or a nonsense mu...

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Detalles Bibliográficos
Publicado en:EMBO J
Main Authors: Lim, S, Mullins, J J, Chen, C M, Gross, K W, Maquat, L E
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1989
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC401267/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2573525/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb08401.x
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