The human poly(ADP-ribose) polymerase nuclear localization signal is a bipartite element functionally separate from DNA binding and catalytic activity.

Poly(ADP-ribose) polymerase (PARP, EC 2.4.2.30) is a zinc finger DNA-binding protein involved in DNA repair processes in eukaryotes. By deletion and extensive site-directed mutagenesis, its DNA-binding domain fused to the N-terminus of beta-galactosidase was shown to contain a nuclear localization s...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Schreiber, V, Molinete, M, Boeuf, H, de Murcia, G, Ménissier-de Murcia, J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1992
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC556860/
https://ncbi.nlm.nih.gov/pubmed/1505517
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