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The Cardiomyopathy-Associated K15N Mutation in Tropomyosin Alters Actin Filament Pointed End Dynamics

Correct assembly of thin filaments composed of actin and actin-binding proteins is of crucial importance for properly functioning muscle cells. Tropomyosin (Tpm) mediates the binding of tropomodulin (Tmod) and leiomodin (Lmod) at the slow-growing, or pointed, ends of the thin filaments. Together the...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Arch Biochem Biophys
Egile Nagusiak: Colpan, Mert, Ly, Thu, Grover, Samantha, Tolkatchev, Dmitri, Kostyukova, Alla S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568491/
https://ncbi.nlm.nih.gov/pubmed/28732641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2017.07.006
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