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The Cardiomyopathy-Associated K15N Mutation in Tropomyosin Alters Actin Filament Pointed End Dynamics
Correct assembly of thin filaments composed of actin and actin-binding proteins is of crucial importance for properly functioning muscle cells. Tropomyosin (Tpm) mediates the binding of tropomodulin (Tmod) and leiomodin (Lmod) at the slow-growing, or pointed, ends of the thin filaments. Together the...
Gardado en:
| Publicado en: | Arch Biochem Biophys |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5568491/ https://ncbi.nlm.nih.gov/pubmed/28732641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2017.07.006 |
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