Nalaganje...
Pocket detection and interaction-weighted ligand-similarity search yields novel high-affinity binders for Myocilin-OLF, a protein implicated in glaucoma
Traditional structure and ligand based virtual screening approaches rely on the availability of structural and ligand binding information. To overcome this limitation, hybrid approaches were developed that relied on extraction of ligand binding information from proteins sharing similar folds and hen...
Shranjeno v:
| izdano v: | Bioorg Med Chem Lett |
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| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5568477/ https://ncbi.nlm.nih.gov/pubmed/28739043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2017.07.035 |
| Oznake: |
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