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Mutations in T7 RNA polymerase that support the proposal for a common polymerase active site structure.
In order to test the proposal that most nucleotide polymerases share a common active site structure and folding topology, we have generated 22 mutations of residues within motifs A, B and C of T7 RNA polymerase (RNAP). Characterization of these T7 RNAP mutants showed the following: (i) most of the m...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | EMBO J |
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| Κύριοι συγγραφείς: | , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group
1992
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC556837/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1396570/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1992.tb05462.x |
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