Interferon-γ Represses M2 Gene Expression in Human Macrophages by Disassembling Enhancers Bound by the Transcription Factor MAF

Mechanisms by which interferon (IFN)-γ activates genes to promote macrophage activation are well studied, but little is known about mechanisms and functions of IFN-γ-mediated gene repression. We used an integrated transcriptomic and epigenomic approach to analyze chromatin accessibility, histone mod...

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Publicado no:Immunity
Main Authors: Kang, Kyuho, Park, Sung Ho, Chen, Janice, Qiao, Yu, Giannopoulou, Eugenia, Berg, Karen, Hanidu, Adedayo, Li, Jun, Nabozny, Gerald, Kang, Keunsoo, Park-Min, Kyung-Hyun, Ivashkiv, Lionel B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568089/
https://ncbi.nlm.nih.gov/pubmed/28813657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2017.07.017
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