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Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation
Interferon-γ (IFN-γ) primes macrophages for enhanced inflammatory activation by Toll-like receptors (TLRs) and microbial killing, but little is known about the regulation of cell metabolism or mRNA translation during priming. We found that IFN-γ regulates human macrophage metabolism and translation...
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| Publicado no: | Nat Immunol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4509841/ https://ncbi.nlm.nih.gov/pubmed/26147685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3205 |
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