To translate, or not to translate: viral and host mRNA regulation by interferon-stimulated genes

Type I interferon (IFN) is one of the first lines of cellular defense against viral pathogens. As a result of IFN signaling, a wide array of IFN-stimulated gene (ISG) products is upregulated to target different stages of the viral life cycle. We review recent findings implicating a subset of ISGs in...

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Bibliographic Details
Published in:Trends Cell Biol
Main Authors: Li, Melody M.H., MacDonald, Margaret R., Rice, Charles M.
Format: Artigo
Language:Inglês
Published: Elsevier Ltd. 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441850/
https://ncbi.nlm.nih.gov/pubmed/25748385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2015.02.001
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