Mechanism for discrimination between viral and host mRNA in interferon-treated cells.

In extracts of interferon-treated HeLa cells, RNA covalently linked to double-stranded RNA (dsRNA) is preferentially degraded compared with mRNA not linked in dsRNA. This was established by following the degradation of poly(A)-containing mRNA annealed with poly(U), of poly(C)-containing encephalomyo...

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Bibliographic Details
Main Authors: Nilsen, T W, Baglioni, C
Format: Artigo
Language:Inglês
Published: 1979
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC383655/
https://ncbi.nlm.nih.gov/pubmed/223150
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