Mechanism for discrimination between viral and host mRNA in interferon-treated cells.
In extracts of interferon-treated HeLa cells, RNA covalently linked to double-stranded RNA (dsRNA) is preferentially degraded compared with mRNA not linked in dsRNA. This was established by following the degradation of poly(A)-containing mRNA annealed with poly(U), of poly(C)-containing encephalomyo...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1979
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383655/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/223150/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.6.2600 |
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