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Mass Spectrometry Based Proteomics Study of Cisplatin-Induced DNA-Protein Cross-Linking in Human Fibrosarcoma (HT1080) Cells

Platinum-based antitumor drugs such as 1,1,2,2-cis-diamminedichloroplatinum(II) (cisplatin), carboplatin, and oxaliplatin are currently used to treat nearly 50% of all cancer cases, and novel platinum based agents are under development. The antitumor effects of cisplatin and other platinum compounds...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Chem Res Toxicol
Hauptverfasser: Ming, Xun, Michaelson-Richie, Erin D., Groehler, Arnold, Villalta, Peter W., Campbell, Colin, Tretyakova, Natalia Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567688/
https://ncbi.nlm.nih.gov/pubmed/28282121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.6b00389
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