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Covalent DNA-Protein Cross-linking by Phosphoramide Mustard and Nornitrogen Mustard in Human Cells
N,N-bis-(2-chloroethyl)-phosphorodiamidic acid (phosphoramide mustard, PM) and N,N-bis-(2-chloroethyl)-ethylamine (nornitrogen mustard, NOR) are the two biologically active metabolites of cyclophosphamide, a DNA alkylating drug commonly used to treat lymphoma, breast cancer, certain brain cancers, a...
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| Udgivet i: | Chem Res Toxicol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4755881/ https://ncbi.nlm.nih.gov/pubmed/26692166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.5b00430 |
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