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Cross-Linking of the DNA Repair Protein O(6)-Alkylguanine DNA Alkyltransferase to DNA in the Presence of Cisplatin
1,1,2,2- Cis-diamminedichloroplatinum (II) (cisplatin) is a chemotherapeutic agent widely used in the clinic to treat various cancers. The antitumor activity of cisplatin is generally attributed to its ability to form intrastrand and interstrand DNA-DNA cross-links via sequential platination of two...
Gardado en:
| Publicado en: | DNA Repair (Amst) |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8177102/ https://ncbi.nlm.nih.gov/pubmed/32283495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2020.102840 |
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