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Crystal Structure of Leiomodin 2 in Complex with Actin: A Structural and Functional Reexamination

Leiomodins (Lmods) are a family of actin filament nucleators related to tropomodulins (Tmods), which are pointed end-capping proteins. Whereas Tmods have alternating tropomyosin- and actin-binding sites (TMBS1, ABS1, TMBS2, ABS2), Lmods lack TMBS2 and half of ABS1, and present a C-terminal extension...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Boczkowska, Malgorzata, Yurtsever, Zeynep, Rebowski, Grzegorz, Eck, Michael J., Dominguez, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567609/
https://ncbi.nlm.nih.gov/pubmed/28834725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.07.007
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