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Structural analysis of the transitional state of Arp2/3 complex activation by two actin-WCAs
Actin filament nucleation and branching by Arp2/3 complex is activated by nucleation-promoting factors (NPFs), whose C-terminal WCA region contains binding sites for actin (W) and Arp2/3 complex (CA). It is debated whether one or two NPFs are required for activation. Here, we present conclusive evid...
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| Publicado en: | Nat Commun |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4364448/ https://ncbi.nlm.nih.gov/pubmed/24518936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4308 |
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