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X-ray Scattering Study of Activated Arp2/3 Complex with Bound Actin-WCA

Previous structures of Arp2/3 complex, determined in the absence of a nucleation-promoting factor and actin, reveal its inactive conformation. The study of the activated structure has been hampered by uncontrollable polymerization. We have engineered a stable activated complex consisting of Arp2/3 c...

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Detalhes bibliográficos
Main Authors: Boczkowska, Malgorzata, Rebowski, Grzegorz, Petoukhov, Maxim V., Hayes, David B., Svergun, Dmitri I., Dominguez, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849165/
https://ncbi.nlm.nih.gov/pubmed/18462674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2008.02.013
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