Yeast mitochondrial DNA mutators with deficient proofreading exonucleolytic activity.

The MIP1 gene which encodes yeast mitochondrial DNA polymerase possesses in its N-terminal region the three motifs (Exo1, Exo2 and Exo3) which characterize the 3'-5' exonucleolytic domain of many DNA polymerases. By site directed mutagenesis we have substituted alanine or glycine residues for conser...

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Bibliografische gegevens

Gepubliceerd in:	EMBO J
Hoofdauteurs:	Foury, F, Vanderstraeten, S
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Nature Publishing Group 1992
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC556747/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1321035/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1992.tb05337.x
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