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Yeast mitochondrial DNA mutators with deficient proofreading exonucleolytic activity.
The MIP1 gene which encodes yeast mitochondrial DNA polymerase possesses in its N-terminal region the three motifs (Exo1, Exo2 and Exo3) which characterize the 3'-5' exonucleolytic domain of many DNA polymerases. By site directed mutagenesis we have substituted alanine or glycine residues...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1992
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC556747/ https://ncbi.nlm.nih.gov/pubmed/1321035 |
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