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Mitogen activated protein (MAP) kinase transforms tau protein into an Alzheimer-like state.

The microtubule-associated protein tau is a major component of the paired helical filaments (PHFs) observed in Alzheimer's disease brains. The pathological tau is distinguished from normal tau by its state of phosphorylation, higher apparent M(r) and reaction with certain antibodies. However, t...

詳細記述

保存先:
書誌詳細
主要な著者: Drewes, G, Lichtenberg-Kraag, B, Döring, F, Mandelkow, E M, Biernat, J, Goris, J, Dorée, M, Mandelkow, E
フォーマット: Artigo
言語:Inglês
出版事項: 1992
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC556680/
https://ncbi.nlm.nih.gov/pubmed/1376245
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