Mitogen activated protein (MAP) kinase transforms tau protein into an Alzheimer-like state.

The microtubule-associated protein tau is a major component of the paired helical filaments (PHFs) observed in Alzheimer's disease brains. The pathological tau is distinguished from normal tau by its state of phosphorylation, higher apparent M(r) and reaction with certain antibodies. However, the pr...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Drewes, G, Lichtenberg-Kraag, B, Döring, F, Mandelkow, E M, Biernat, J, Goris, J, Dorée, M, Mandelkow, E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC556680/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1376245/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1992.tb05272.x
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