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Mitogen activated protein (MAP) kinase transforms tau protein into an Alzheimer-like state.

The microtubule-associated protein tau is a major component of the paired helical filaments (PHFs) observed in Alzheimer's disease brains. The pathological tau is distinguished from normal tau by its state of phosphorylation, higher apparent M(r) and reaction with certain antibodies. However, t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Drewes, G, Lichtenberg-Kraag, B, Döring, F, Mandelkow, E M, Biernat, J, Goris, J, Dorée, M, Mandelkow, E
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1992
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC556680/
https://ncbi.nlm.nih.gov/pubmed/1376245
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