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PDGF-BB enhances collagen gel contraction through a PI3K-PLCγ-PKC-cofilin pathway
Cell-mediated contraction of collagenous matrices is modulated by various growth factors and cytokines, such as platelet-derived growth factor-BB (PDGF-BB). Here we used a genetic cell model to delineate defined signaling pathways that enhance collagen gel contraction downstream of ligand-stimulated...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5566449/ https://ncbi.nlm.nih.gov/pubmed/28827622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08411-1 |
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