PDGF-BB enhances collagen gel contraction through a PI3K-PLCγ-PKC-cofilin pathway

Cell-mediated contraction of collagenous matrices is modulated by various growth factors and cytokines, such as platelet-derived growth factor-BB (PDGF-BB). Here we used a genetic cell model to delineate defined signaling pathways that enhance collagen gel contraction downstream of ligand-stimulated...

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Foilsithe in:Sci Rep
Main Authors: Reyhani, Vahid, Tsioumpekou, Maria, van Wieringen, Tijs, Rask, Lars, Lennartsson, Johan, Rubin, Kristofer
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2017
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5566449/
https://ncbi.nlm.nih.gov/pubmed/28827622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08411-1
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