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Diglycosyl diselenides alter redox homeostasis and glucose consumption of infective African trypanosomes

With the aim to develop compounds able to target multiple metabolic pathways and, thus, to lower the chances of drug resistance, we investigated the anti-trypanosomal activity and selectivity of a series of symmetric diglycosyl diselenides and disulfides. Of 18 compounds tested the fully acetylated...

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Detaylı Bibliyografya
Yayımlandı:Int J Parasitol Drugs Drug Resist
Asıl Yazarlar: Franco, Jaime, Sardi, Florencia, Szilágyi, László, Kövér, Katalin E., Fehér, Krisztina, Comini, Marcelo A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5565762/
https://ncbi.nlm.nih.gov/pubmed/28826037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2017.08.001
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