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Diglycosyl diselenides alter redox homeostasis and glucose consumption of infective African trypanosomes
With the aim to develop compounds able to target multiple metabolic pathways and, thus, to lower the chances of drug resistance, we investigated the anti-trypanosomal activity and selectivity of a series of symmetric diglycosyl diselenides and disulfides. Of 18 compounds tested the fully acetylated...
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| Publicado no: | Int J Parasitol Drugs Drug Resist |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5565762/ https://ncbi.nlm.nih.gov/pubmed/28826037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2017.08.001 |
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