Humanization of JAA-F11, a Highly Specific Anti-Thomsen-Friedenreich Pancarcinoma Antibody and InVitro Efficacy Analysis

JAA-F11 is a highly specific mouse monoclonal to the Thomsen-Friedenreich Antigen (TF-Ag) which is an alpha-O-linked disaccharide antigen on the surface of ~80% of human carcinomas, including breast, lung, colon, bladder, ovarian, and prostate cancers, and is cryptic on normal cells. JAA-F11 has pot...

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Publicado en:Neoplasia
Main Authors: Tati, Swetha, Fisk, John C., Abdullah, Julia, Karacosta, Loukia, Chrisikos, Taylor, Philbin, Padraic, Morey, Susan, Ghazal, Diala, Zazala, Fatma, Jessee, Joseph, Quataert, Sally, Koury, Stephen, Moreno, David, Eng, Jing Ying, Glinsky, Vladislav V., Glinskii, Olga V., Sesay, Muctarr, Gebhard, Anthony W., Birthare, Karamveer, Olson, James R., Rittenhouse-Olson, Kate
Formato: Artigo
Idioma:Inglês
Publicado: Neoplasia Press 2017
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Original article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5565633/
https://ncbi.nlm.nih.gov/pubmed/28830009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2017.07.001
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