Humanization of JAA-F11, a Highly Specific Anti-Thomsen-Friedenreich Pancarcinoma Antibody and InVitro Efficacy Analysis

JAA-F11 is a highly specific mouse monoclonal to the Thomsen-Friedenreich Antigen (TF-Ag) which is an alpha-O-linked disaccharide antigen on the surface of ~80% of human carcinomas, including breast, lung, colon, bladder, ovarian, and prostate cancers, and is cryptic on normal cells. JAA-F11 has pot...

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發表在:Neoplasia
Main Authors: Tati, Swetha, Fisk, John C., Abdullah, Julia, Karacosta, Loukia, Chrisikos, Taylor, Philbin, Padraic, Morey, Susan, Ghazal, Diala, Zazala, Fatma, Jessee, Joseph, Quataert, Sally, Koury, Stephen, Moreno, David, Eng, Jing Ying, Glinsky, Vladislav V., Glinskii, Olga V., Sesay, Muctarr, Gebhard, Anthony W., Birthare, Karamveer, Olson, James R., Rittenhouse-Olson, Kate
格式: Artigo
語言:Inglês
出版: Neoplasia Press 2017
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Original article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5565633/
https://ncbi.nlm.nih.gov/pubmed/28830009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2017.07.001
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