Humanization of JAA-F11, a Highly Specific Anti-Thomsen-Friedenreich Pancarcinoma Antibody and InVitro Efficacy Analysis

JAA-F11 is a highly specific mouse monoclonal to the Thomsen-Friedenreich Antigen (TF-Ag) which is an alpha-O-linked disaccharide antigen on the surface of ~80% of human carcinomas, including breast, lung, colon, bladder, ovarian, and prostate cancers, and is cryptic on normal cells. JAA-F11 has pot...

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Bibliographic Details
Published in:Neoplasia
Main Authors: Tati, Swetha, Fisk, John C., Abdullah, Julia, Karacosta, Loukia, Chrisikos, Taylor, Philbin, Padraic, Morey, Susan, Ghazal, Diala, Zazala, Fatma, Jessee, Joseph, Quataert, Sally, Koury, Stephen, Moreno, David, Eng, Jing Ying, Glinsky, Vladislav V., Glinskii, Olga V., Sesay, Muctarr, Gebhard, Anthony W., Birthare, Karamveer, Olson, James R., Rittenhouse-Olson, Kate
Format: Artigo
Language:Inglês
Published: Neoplasia Press 2017
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Original article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5565633/
https://ncbi.nlm.nih.gov/pubmed/28830009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2017.07.001
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