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PUM1 is a biphasic negative regulator of innate immunity genes by suppressing LGP2
PUM1 is an RNA binding protein shown to regulate the stability and function of mRNAs bearing a specific sequence. We report the following: (i) A key function of PUM1 is that of a repressor of key innate immunity genes by repressing the expression of LGP2. Thus, between 12 and 48 hours after transfec...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5565464/ https://ncbi.nlm.nih.gov/pubmed/28760986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1708713114 |
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