Pharmacological activation of estrogen receptor beta augments innate immunity to suppress cancer metastasis

Metastases constitute the greatest causes of deaths from cancer. However, no effective therapeutic options currently exist for cancer patients with metastasis. Estrogen receptor β (ERβ), as a member of the nuclear receptor superfamily, shows potent tumor-suppressive activities in many cancers. To in...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Zhao, Linjie, Huang, Shuang, Mei, Shenglin, Yang, Zhengnan, Xu, Lian, Zhou, Nianxin, Yang, Qilian, Shen, Qiuhong, Wang, Wei, Le, Xiaobing, Lau, Wayne Bond, Lau, Bonnie, Wang, Xin, Yi, Tao, Zhao, Xia, Wei, Yuquan, Warner, Margaret, Gustafsson, Jan-Åke, Zhou, Shengtao
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2018
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PNAS Plus
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910874/
https://ncbi.nlm.nih.gov/pubmed/29592953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1803291115
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