The RNA binding protein SORBS2 suppresses metastatic colonization of ovarian cancer by stabilizing tumor-suppressive immunomodulatory transcripts

BACKGROUND: Ovarian cancer constitutes one of the most lethal gynecologic malignancies for females. Currently, early detection strategies and therapeutic options for ovarian cancer are far from satisfactory, leading to high diagnosis rates at late stages and disease relapses. New avenues of therapy...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Zhao, Linjie, Wang, Wei, Huang, Shuang, Yang, Zhengnan, Xu, Lian, Yang, Qilian, Zhou, Xiu, Wang, Jinjin, Shen, Qiuhong, Wang, Chenlu, Le, Xiaobing, Feng, Min, Zhou, Nianxin, Lau, Wayne Bond, Lau, Bonnie, Yao, Shaohua, Yi, Tao, Wang, Xin, Zhao, Xia, Wei, Yuquan, Zhou, Shengtao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5857099/
https://ncbi.nlm.nih.gov/pubmed/29548303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1412-6
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