The RNA binding protein SORBS2 suppresses metastatic colonization of ovarian cancer by stabilizing tumor-suppressive immunomodulatory transcripts

BACKGROUND: Ovarian cancer constitutes one of the most lethal gynecologic malignancies for females. Currently, early detection strategies and therapeutic options for ovarian cancer are far from satisfactory, leading to high diagnosis rates at late stages and disease relapses. New avenues of therapy...

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Bibliografiske detaljer
Udgivet i:Genome Biol
Main Authors: Zhao, Linjie, Wang, Wei, Huang, Shuang, Yang, Zhengnan, Xu, Lian, Yang, Qilian, Zhou, Xiu, Wang, Jinjin, Shen, Qiuhong, Wang, Chenlu, Le, Xiaobing, Feng, Min, Zhou, Nianxin, Lau, Wayne Bond, Lau, Bonnie, Yao, Shaohua, Yi, Tao, Wang, Xin, Zhao, Xia, Wei, Yuquan, Zhou, Shengtao
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5857099/
https://ncbi.nlm.nih.gov/pubmed/29548303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1412-6
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