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Ferroptosis and autophagy induced cell death occur independently after siramesine and lapatinib treatment in breast cancer cells
Ferroptosis is a cell death pathway characterized by iron-dependent accumulation of reactive oxygen species (ROS) within the cell. The combination of siramesine, a lysosome disruptor, and lapatinib, a dual tyrosine kinase inhibitor, has been shown to synergistically induce cell death in breast cance...
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| 發表在: | PLoS One |
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| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5565111/ https://ncbi.nlm.nih.gov/pubmed/28827805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182921 |
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