Tyrosine kinase receptor EGFR regulates the switch in cancer cells between cell survival and cell death induced by autophagy in hypoxia

Autophagy is an intracellular lysosomal degradation pathway where its primary function is to allow cells to survive under stressful conditions. Autophagy is, however, a double-edge sword that can either promote cell survival or cell death. In cancer, hypoxic regions contribute to poor prognosis due...

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Bibliographische Detailangaben
Veröffentlicht in:Autophagy
Hauptverfasser: Chen, Yongqiang, Henson, Elizabeth S., Xiao, Wenyan, Huang, Daniel, McMillan-Ward, Eileen M., Israels, Sara J., Gibson, Spencer B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2016
Schlagworte:
Basic Research Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922445/
https://ncbi.nlm.nih.gov/pubmed/27166522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1164357
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