Tyrosine kinase receptor EGFR regulates the switch in cancer cells between cell survival and cell death induced by autophagy in hypoxia

Autophagy is an intracellular lysosomal degradation pathway where its primary function is to allow cells to survive under stressful conditions. Autophagy is, however, a double-edge sword that can either promote cell survival or cell death. In cancer, hypoxic regions contribute to poor prognosis due...

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Bibliographic Details
Published in:Autophagy
Main Authors: Chen, Yongqiang, Henson, Elizabeth S., Xiao, Wenyan, Huang, Daniel, McMillan-Ward, Eileen M., Israels, Sara J., Gibson, Spencer B.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2016
Subjects:
Basic Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922445/
https://ncbi.nlm.nih.gov/pubmed/27166522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1164357
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