HAF mediates the evasive resistance of anti-angiogenesis TKI through disrupting HIF-1α and HIF-2α balance in renal cell carcinoma

Anti-angiogenesis has emerged as a standard of care for metastatic renal cell carcinoma. However, long-lasting efficacy is seldom reached, and evasive resistance eventually occurs under anti-angiogenic tyrosine kinase inhibitor (TKI) therapy. To establish new therapeutic strategies, investigating th...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lai, Xiang-Me, Liu, Shu-Yu, Tsai, Yi-Ta, Sun, Guang-Huan, Chang, Sun-Yran, Huang, Shih-Ming, Cha, Tai-Lung
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564801/
https://ncbi.nlm.nih.gov/pubmed/28572533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17923
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