HAF drives the switch of HIF-1α to HIF-2α by activating the NF-κB pathway, leading to malignant behavior of T24 bladder cancer cells

Hypoxia is a characteristic feature of solid tumors, leading to malignant behavior. During this process, HIF family members (HIFs) and the NF-κB pathway are activated. In addition, the hypoxia-associated factor (HAF) is reported to participate in the regulation of HIFs. However, the precise relation...

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Main Authors: GUAN, ZHENFENG, DING, CHEN, DU, YIQING, ZHANG, KAI, ZHU, JIAN NING, ZHANG, TINGTING, HE, DALIN, XU, SHAN, WANG, XINYANG, FAN, JINHAI
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898811/
https://ncbi.nlm.nih.gov/pubmed/24316875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2013.2210
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