Inflammatory microRNA-194 and -515 attenuate the biosynthesis of chondroitin sulfate during human intervertebral disc degeneration

Intervertebral disc degeneration (IDD) is characterized by dehydration and loss of extracellular matrixes in the nucleus pulposus region. Chondroitin sulfate has been found to be the water-binding molecule that played a key role in IDD. Although investigators have reported that inflammatory cytokine...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Hu, Bo, Xu, Chen, Tian, Ye, Shi, Changgui, Zhang, Ying, Deng, Lianfu, Zhou, Hongyu, Cao, Peng, Chen, Huajiang, Yuan, Wen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2017
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564769/
https://ncbi.nlm.nih.gov/pubmed/28514734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17571
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