Inflammatory microRNA-194 and -515 attenuate the biosynthesis of chondroitin sulfate during human intervertebral disc degeneration

Intervertebral disc degeneration (IDD) is characterized by dehydration and loss of extracellular matrixes in the nucleus pulposus region. Chondroitin sulfate has been found to be the water-binding molecule that played a key role in IDD. Although investigators have reported that inflammatory cytokine...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Hu, Bo, Xu, Chen, Tian, Ye, Shi, Changgui, Zhang, Ying, Deng, Lianfu, Zhou, Hongyu, Cao, Peng, Chen, Huajiang, Yuan, Wen
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564769/
https://ncbi.nlm.nih.gov/pubmed/28514734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17571
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