Protein drug target activation homogeneity in the face of intra-tumor heterogeneity: implications for precision medicine

Introduction: Recent studies indicated tumors may be comprised of heterogeneous molecular subtypes and incongruent molecular portraits may emerge if different areas of the tumor are sampled. This study explored the impact of intra-tumoral heterogeneity in terms of activation/phosphorylation of FDA a...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Parasido, Erika Maria, Silvestri, Alessandra, Canzonieri, Vincenzo, Belluco, Claudio, Diodoro, Maria Grazia, Milione, Massimo, Melotti, Flavia, De Maria, Ruggero, Liotta, Lance, Petricoin, Emanuel F., Pierobon, Mariaelena
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Priority Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564706/
https://ncbi.nlm.nih.gov/pubmed/28159918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14019
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