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Protein drug target activation homogeneity in the face of intra-tumor heterogeneity: implications for precision medicine

Introduction: Recent studies indicated tumors may be comprised of heterogeneous molecular subtypes and incongruent molecular portraits may emerge if different areas of the tumor are sampled. This study explored the impact of intra-tumoral heterogeneity in terms of activation/phosphorylation of FDA a...

詳細記述

保存先:
書誌詳細
出版年:Oncotarget
主要な著者: Parasido, Erika Maria, Silvestri, Alessandra, Canzonieri, Vincenzo, Belluco, Claudio, Diodoro, Maria Grazia, Milione, Massimo, Melotti, Flavia, De Maria, Ruggero, Liotta, Lance, Petricoin, Emanuel F., Pierobon, Mariaelena
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564706/
https://ncbi.nlm.nih.gov/pubmed/28159918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14019
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