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Involvement of p38-βTrCP-Tristetraprolin-TNFα axis in radiation pneumonitis

Early release of tumor necrosis factor-alpha (TNF-α) during radiotherapy of thoracic cancers plays an important role in radiation pneumonitis, whose inhibition may provide lung radioprotection. We previously reported radiation inactivates Tristetraprolin (TTP), a negative regulator of TNF-α synthesi...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Krishnamurthy, Pranathi Meda, Shukla, Shirish, Ray, Paramita, Mehra, Rohit, Nyati, Mukesh K, Lawrence, Theodore S, Ray, Dipankar
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564603/
https://ncbi.nlm.nih.gov/pubmed/28548957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17770
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