Tristetraprolin Mediates Radiation-Induced TNF-α Production in Lung Macrophages

The efficacy of radiation therapy for lung cancer is limited by radiation-induced lung toxicity (RILT). Although tumor necrosis factor-alpha (TNF-α) signaling plays a critical role in RILT, the molecular regulators of radiation-induced TNF-α production remain unknown. We investigated the role of a m...

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Autors principals: Ray, Dipankar, Shukla, Shirish, Allam, Uday Sankar, Helman, Abigail, Ramanand, Susmita Gurjar, Tran, Linda, Bassetti, Michael, Krishnamurthy, Pranathi Meda, Rumschlag, Matthew, Paulsen, Michelle, Sun, Lei, Shanley, Thomas P., Ljungman, Mats, Nyati, Mukesh K., Zhang, Ming, Lawrence, Theodore S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585360/
https://ncbi.nlm.nih.gov/pubmed/23468959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057290
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